Botulinum Neurotoxins: 2157 (Current Topics in Microbiology by Andreas Rummel,Thomas Binz

By Andreas Rummel,Thomas Binz

The super powerful substance botulinum neurotoxin (BoNT) has attracted a lot curiosity in different fields. initially pointed out as reason for the infrequent yet lethal affliction botulism, army and terrorist meant to misuse this subtle molecule as organic weapon. This triggered its class as opt for agent classification A via the facilities for ailments keep an eye on and Prevention and the directory within the organic and Toxin guns conference. Later, the civilian use of BoNT as lengthy appearing peripheral muscle relaxant has became this molecule into an integral pharmaceutical around the globe with annual sales >$1.5 billion. additionally simple scientists worth the botulinum neurotoxin as molecular software for dissecting mechanisms of exocytosis. This booklet will disguise the newest molecular info of botulinum neurotoxin, its mechanism of motion in addition to its detection and application.

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